Biophysicist Job Description Sample
Senior Associate Scientist, Assay Development
The development of small-molecule, targeted inhibitors has revolutionized the effective treatment of cancer patients. This Enzymologist / Biochemist / Biophysicist will be based in San Diego, CA and make important contributions to our molecular, biochemical and biophysical understanding of these tumor cell signaling pathways through the development of robust, automated biochemical and binding assays and selectivity screens to drive the SAR for inhibitors (or activators) of cancer targets. The scientist will develop a variety of assays and provide high quality data that drives decisions on projects and seeks to better understand the signaling pathways involved in cancer malignancies.
Provides expertise to the development and implementation of robust, automated biochemical and binding assays
Generates high quality data, performs complex data analyses and correlates in vitro and in vivo SAR for small molecule projects
Develops and implements innovative binding and selectivity screens for compound progression
Works with CROs to effectively manage resources for project activities
- BS/MS Enzymologist / Biochemist / Biophysicist with experience in cancer drug discovery and the development of assays and bioanalytical methods for preclinical drug discovery and hit-to-lead optimization.
- BS with 3-5 years or MS with 1-2 years of experience.
- BS/MS Biochemist with experience in cancer drug discovery and knowledge of cell signaling pathways.Must have strong technical abilities and skilled in developing and performing automated plate-based pharmacology assays, enzyme kinetics and understanding inhibitor SAR. Biophysical assay experience (e.g. SPR, thermal shift etc.) is desired. Preference for candidates with pharmaceutical/biotech drug discovery experience in evaluating small-molecule inhibitors against enzyme targets, including protein kinases.
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.
Other Job Details:
- Eligible for Employee Referral Bonus
N (Other) (United States of America)
Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.
Making better hires starts with building better job descriptions
- Browse 100s of templates across 40+ industries
- Customize your template with your company info & job requirements
- Post it to 20+ job boards in seconds – for FREE!