Cell Inspector Job Description Sample
Quality Inspector - 2Nd Shift - Barrel Cell - Harbison-Fischer (1195-146)
Quality Inspector will read blueprints and specifications. Monitor operations to ensure that they meet production standards. Recommend adjustments to the assembly or production process. Inspect, test, or measure materials or products being produced. Also, good communication skills and entry level computer skills.
Perform "First Piece" inspection throughout assigned Product Group Line / Value Stream
Perform "Final" inspection throughout assigned Product Group Line / Value Stream
Assist Product Group Line / Value Stream in quality problem resolution
Perform in-process audits throughout Product Group Line / Value Stream
Document all inspection and testing results
Maintain all document files and test records in accurate manner
Initiate non-conformance report and assist in corrective/preventive action report determination
Perform 100% inspection/sorting as required
Assist with writing and updating of inspection procedures and checklists
Support actively all H-F Continuous Improvement efforts
Verify with Gage Calibration that all inspection standards/gages are calibrated and kept up to date
Observe plant safety rules and report any unsafe conditions
Perform all other duties as assigned or needed
High School Diploma or Equivalent
Must have at least 1 years experience in industrial manufacturing environment
Experience in quality inspection preferred
Mechanical aptitude desired
Good English written and verbal communication skills
Must know how to use and read Calipers, Depth Micrometers, Tenth Micrometers, Micrometers, Rulers, Spring Calipers and Telescope Gages
Must understand fractions/decimals and how to convert from one to the other would be a plus
Ability to read and interpret blue prints
Must have good computer skills and knowledge of computer software
Must be willing to work overtime as required
Must be self-directed, well-organized and detail-oriented
Excellent interpersonal skills
Must be able to pass a background and drug screen
Cell Processing Specialist Car-T Cell Therapy - Morris Plains, NJ
Cell Processing Specialist CAR-T Cell Therapy - Morris Plains, NJ
Novartis is a global healthcare company based in Switzerland that provides solutions to address the evolving needs of patients worldwide. Novartis recently received the first ever FDA approval for a CAR-T cell therapy for children and young adults with B-cell precursor acute lymphoblastic leukemia (ALL) that is refractory or has relapsed at least twice; a novel immunocellular therapy, a one-time treatment that uses a patient's own T cells to fight cancer, and is the first therapy based on gene transfer approved by the FDA. Therapy will be manufactured for individual patients using their own cells at the Novartis Morris Plains, New Jersey facility where Novartis continues to advance its CAR-T manufacturing expertise. The Morris Plains site plans to hire over 300 Quality, Production, Supply Chain and Bioanalytics associates in the next 10-12 months.
Due to the nature of the starting materials (patient cells) the Cell processing Specialist role requires the highest level of proficiency and ownership. The Specialist will be responsible for end to end processing and verification of patient derived clinical and commercial cellular immunotherapy products.
Specific responsibilities will include:
End to end ownership for the processing of the assigned patient starting material in the clean room environment.
Maintain and prepare equipment/environment for use.
Document all steps in the assigned Batch record in line with GMP requirements.
Conduct all necessary processing/verification steps for the assigned lot with the highest skill level of aseptic technique.
Assist on Deviation Investigations, Change Controls, Safety Inspections and CAPAs.
Perform execution of assigned qualification/ validation activities.
Be responsible for successful on time completion of a required training curriculum composed of Global Operating Procedures (GOPs), Standard Operating Procedures (SOPs), Aseptic Techniques, Gowning Qualifications and other relevant training, including HSE for the specific role.
Perform other duties as assigned. Examples might be: successful completion of assigned PU project initiatives and/or work stream tasks, such as process improvements, efficiencies, Innovation Quality Productivity (IQP).
Maintain an "audit ready" module.
Selected associates must:
Be able to gown aseptically and work in a clean room environment (ISO 8, 7 and ISO 5) area for extended periods of time.
Be able to work with automated cell processing equipment such as Elutra, CS5, or Sepax.
Be knowledgeable in the use of production related IT systems such as SAP and MES.
Possess sound cell biological decision making.
Cell Production Operator
Panasonic Corporation is working to manufacture photovoltaic (PV) modules and cells for solar panels at Tesla's factory in Buffalo, New York.
Panasonic's role is to manufacture and supply our SHJ (Silicon Heterojunction) PV cells and modules that feature industry-leading module conversion efficiency and outstanding temperature coefficient characteristics, which result in more power than similarly rated solar panels.
This collaboration makes optimum use of both companies' strengths to enhance the competitiveness of their products, generating a synergy effect between Panasonic's technological and manufacturing expertise in the photovoltaic business and Tesla's strong sales channels, rich creativity and market-leading, cutting-edge innovation.
As a valued partner and strong customer of Panasonic, Tesla is making a long-term purchase commitment for products manufactured at the Riverbend factory.
This is an opportunity that's made to order for a career-minded individual who wants to make a difference and contribute to a more sustainable future based on renewable energy. Join this creative technology collaboration and grow with it as operations continue to expand.
The most successful employees at PESSNY are results driven and able to continuously adapt to an ever-changing startup environment. They report to work on time and never settle for anything less than the best. They work well in a team environment but also have the drive to succeed when they are on their own. A strong focus on fairness and honesty with a humble attitude are what defines our top performers. Is that you?
Currently, PESSNY has an immediate opening available for a Cell Production Operator.
What You'll Get to Do:
Key tasks with respect to the Cell Production Department:
Meet department KPI's:
Production plan achievement rate (On-time delivery)
Productivity (Output per head)
Production loss (Failure cost)
Production cost (Direct/Indirect labor, Depreciation, Indirect material, Power, Maintenance & Repair...)
Inventory amount and Inventory difference
Support production material movement and processes based on work standards, work instructions, process inspection standards
Support PC Technicians and Engineer in: Production planning progress control, Raw materials, WIP and FG control/stock reduction, IDM manage & cost reduction, SAP updating & MES management, new technology installation
Report progress and issues to PC Tech and QC
What You'll Bring:
Education & Experience
Education: High school degree and above
Experience in manufacturing facility
Problem solving power
Sense of responsibility
Ability to collaborate with relevant departments
Equipment maintenance skills
High awareness about safety
Basic PC work
Employee lifting up to 25 pounds, transporting work
Handles general chemicals and gas used in solar cell manufacturing.
Mainly in the clean room.
The noise level of working environment is usually moderate.
Irregular shift (Saturdays, Sundays and public holidays)
In-house inspector registration required
Candidates must be willing to work in a clean room environment, wearing coveralls, hoods, booties, safety glasses and gloves.
No cosmetics shall be worn in the cleanrooms. This includes: lipstick, eye shadow, eyebrow pencil, mascara, eye liner, false eye lashes, fingernail polish, hair spray, mousse, or the heavy use of aerosols, after shaves and perfumes.
This position will require exposure to strong magnets that will interfere with pacemaker/defibrillator function. For safety reasons, candidates with a pacemaker/defibrillator cannot be considered for this position.
In addition to an environment that's as innovative as our products, we offer competitive salaries and benefits.
What We Offer:
Family like environment with an entrepreneurial spirit
Collaborative culture that thrives on innovation and new ideas
Rewards and recognition for great achievements
Growth opportunities for career development
Flexible work arrangements to help balance life and work
Competitive benefits and compensation package
Panasonic is proud to be an Equal Opportunity/Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender identity, sex, sexual orientation, national origin, disability status, protected veteran status, and any other characteristic protected by law or company policy. All qualified individuals are required to perform the essential functions of the job with or without reasonable accommodation.
Pre-employment drug testing is required for safety sensitive positions or as may otherwise be required by contract or law. Due to the high volume of responses, we will only be able to respond to candidates of interest. All candidates must have valid authorization to work in the U.S. Thank you for your interest in Panasonic Corporation of North America.
Location/Division:Buffalo, NY, USAJob Requisition:HF7015
QC Cell Therapy Technician
The incumbent in this position is responsible for highly complex and specialized testing of cellular products for clinical trials and commercial operations. In addition, this individual will be responsiblefor Quality Control testing of the GMP facility, and projects manufactured therein, to ensure it is in control and in compliance with applicable regulations. The individualwill report to the GMP Quality Control Supervisor. The individual filling this position will be an integral member of a team working together to produce the highest quality clinical material for novel cellular therapies.
Perform duties as dictated by standard operating procedures (SOPs) for Quality Control and release testing of cellular product manufacturing and under G'X'P (GLP,GTP, GMP, GDP) guidelines as directed. Perform sterility, endotoxin, cell characterization by flow cytometry, and other required testing to support in-process testing and final product release.
Ship samples to outside vendors for quality control testing.
Operate Quality Control instrumentation needed for release testing such as cell counting devices, micropipettes, Biological Safety Cabinets, flow cytometers, and endotoxin testing devices.
Serve as a resource to the GMP Quality Control supervisor in identifying and assessing the appropriate complement of resources and support needed to successfully complete quality control related work.
Maintain responsibility and confidentiality for patient identification, specimen labeling and specimen verification. Use knowledge of laboratory safety and infection control procedures and practices to safely perform required work including universal precautions and hazardous chemical handling.
Perform routine environmental monitoring of the GMP facility. Perform duties in a clean room environment while fully gowned (hood, mask, coverall, boots, gloves, etc.) following GMP guidelines.
Operate instrumentation needed for environmental monitoring.
Perform Quality Control activities for the facility, including checking expiration dates for supplies and tracking maintenance schedule for equipment, including biosafety cabinets, pipettes, centrifuges and other specialized equipment.
Maintain sufficient inventory of supplies and reagents for performance of duties; clean and maintain laboratory equipment in good working order
Maintenance of Quality Control-related procedures, documentation, and equipment. Notification of management of any Quality Control-related out of specification (OOS) result.
Assistance in writing and review of validations, research plans and reports, SOPs, and batch records as required.
Work with GMP QC Supervisor to ensure the facility is in compliance for governing regulations. Help to maintain orderly lab spaces.
Participate in lab inspections and work with inspectors as needed
Use dexterity, knowledge, and ability to complete assigned laboratory tasks and skills, with attention to detail and compliance with all appropriate laboratory regulatory and safety requirements.
Preferred Skills and Work Experience:- Up to two years of Quality Control experience, preferably in a GMP/regulated environment.- Good communication skills and the ability to work independently as well as part of team. Communicate and interact in a professional and courteous manner with co-workers, and others.- Must be team oriented and able to work in a highly collaborative work environment to complete complex tasks.- Must be able to manage multiple and rapidly changing priorities and have ability to quickly learn new skills and concepts.
Perform other related duties incidental to the work described herein.Duke University is an Affirmative Action/Equal Opportunity Employercommitted to providing employment opportunity without regard to anindividual's age, color, disability, gender, gender expression, genderidentity, genetic information, national origin, race, religion, sex,sexual orientation, or veteran status.
Duke aspires to create a community built on collaboration, innovation,creativity, and belonging. Our collective success depends on the robustexchange of ideas—an exchange that is best when the rich diversity ofour perspectives, backgrounds, and experiences flourishes. To achievethis exchange, it is essential that all members of the community feelsecure and welcome, that the contributions of all individuals arerespected, and that all voices are heard. All members of our communityhave a responsibility to uphold these values.
Essential Physical Job Functions:Certain jobs at Duke University and Duke University Health System mayinclude essential job functions that require specific physical and/ormental abilities. Additional information and provision for requests forreasonable accommodation will be provided by each hiring department.
Work requires a bachelor's degree in botany, biology, zoology or otherdirectly related scientific field.
Work requires two years of research experience. A related master'sdegree may offset required years of experience on a 1:1 basis, e.g., atwo year master's degree in lieu of two years of experience.OR AN EQUIVALENT COMBINATION OF RELEVANT EDUCATION AND/OR EXPERIENCE
Team Ldr II Manufacturing ( Cell Lead)
Requisition ID 115360BR Date updated 05/14/2018
Job Title: Team Leader II Manufacturing – RHS
IDS Mechanical Engineering Directorate (MED) has a need for a 1st shift cell leader in the Rapid Hardware Solutions organization (RHS). This position has overall responsibility for manufacturing operation team(s) in a fast paced and dynamic environment and will manage a represented team of assembly operators (assemblers, finishers, inspectors etc.). The individual in this role ensures assembled hardware meets contractual military and industry quality, program cost and schedule requirements by planning, organizing, and directing product flow. This individual will need to actively ensure a quality and safe work environment and be engaged in affordability, quality and safety improvement projects.
U.S. Citizenship status is required as this position will need a U.S. Security Clearance within 1 year of start date.Except in rare circumstances, only U.S. citizens are eligible for a security clearance.
This position can be a Salary Grade G08 or Salary Grade G09. based on the candidate's qualifications as they relate to the skills, experience and responsibility requirements for the position.
Job Duties and Responsibilities:
This role requires daily interaction with other cross-business teams in IDS to maintain and meet organizational goals and objectives of achieving/exceeding cost, quality, delivery, and safety goals. These teams include project management, technical support, manufacturing and design engineering, material control and facility maintenance. Performance criteria for this position include identifying and implementing continuous improvement opportunities using six sigma and lean methodologies.
The position supports deployment of manufacturing operations strategy, control systems, tools and metrics to accurately measure progress, identify defects, determine root cause and develop/implement corrective action plans.
In addition to the above, responsibilities include:
Employee compliance and skills training
Time and attendance tracking
Area layout and flow management
Ensuring the enforcement of company policies and procedures
Quality and Safety audit support
Minimum of 4 years of related work experience in hardware development, production / manufacturing / operations or similar environments
Previous team leadership experience in manufacturing / planning / scheduling / operations or similar environments
Experience working with Microsoft Office, and other business related tools.
Familiarity with Visiprise Management
Experience utilizing lean manufacturing and six sigma concepts with a proven track record of project leadership and improvement implementation.
Previous experience supervising bargaining unit employees
Manufacturing or Industrial Engineering experience in the aerospace/defense industry
Experience utilizing business systems and tools that aid in managing labor, processes, and budgets
Excellent communication (written and verbal)
Solid people management and interpersonal skills; conflict management
Experience making decisions with minimal supervision
Metrics driven and success oriented
Ability to obtain a clearance.
- Bachelor's Degree in Engineering, Business (or related field) or equivalent combination of related experience and education (each two years of related experience can substitute for one year of education).
Business Unit Profile
Headquartered in Tewksbury, Massachusetts, IDS has 32 locations around the world. Its broad portfolio of weapons, sensors and integration systems supports its customer base across multiple mission areas, including air and missile defense systems; missile defense radars; early warning radars; naval ship operating systems; C5ITM products and services; and other advanced technologies. IDS provides affordable, integrated solutions to a broad international and domestic customer base, including the U.S. Missile Defense Agency, the U.S. Armed Forces and the Department of Homeland Security.
Type Of Job
MA - Marlborough
Raytheon is an Equal Opportunity/Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, creed, sex, sexual orientation, gender identity, national origin, disability, or protected Veteran status.
Cell Processing Associate Car-T Cell Therapy Morris Plains, NJ
Cell Processing Associate CAR-T Cell Therapy
The Cell Processing Associate is responsible for intermediate processing of patient derived clinical and commercial cellular immunotherapy products. Due to the nature of the starting material (patient cells) this role requires basic proficiency and ownership of the process.
Intermediate ownership for the processing of the assigned Patient starting material in the clean room environment.
Ability to gown aseptically and work in a clean room environment (ISO 8, 7 and ISO 5) areas for extended periods of time.
Maintains and prepares equipment/environment for use.
Ability to work with automated cell processing equipment such as the wave bioreactor.
Ability to perform in process operations such as: bioreactor sampling, static sampling and in process environmental monitoring.
Knowledgeable in the use of production related IT systems such as SAP and MES.
Documents all steps in the assigned Batch record in line with GMP requirements.
Conduct all necessary processing steps for the assigned lot with highest skill level of aseptic technique.
Assist with deviation investigations and inspections.
Participation in assigned qualification/ validation activities, as necessary.
Responsible for successful on time completion of required training curriculum comprising of the necessary Global Operating Procedures (GOPs), Standard Operating Procedures (SOPs) and Aseptic Techniques, Gowning Qualifications and other relevant training including HSE for the specific role.
Maintains an "audit ready" module.
Perform other duties as assigned; ie. batch record review, process streamline improvements, safety walk-thrus.
Scientist I Single Cell Transcriptomic Approaches To Cell Types In The Mouse Nervous System
The Allen Institute for Brain Science, located in Seattle, Washington, is committed to understanding how the brain works and helping to unlock the mysteries of neurological diseases and disorders affecting millions worldwide.
The Allen Institute is seeking an exceptional candidate who will be part of a Seattle-based multidisciplinary team within the Cell Types Program. The successful candidate will participate in high-throughput single cell transcriptome data generation and analysis to support the effort funded by the newly awarded BRAIN grant from the NIH, which aims to define all cell types in the adult mouse brain. The candidate will be a Ph.D. graduate in life sciences or computational biology and will possess strong experimental and computational skills. She/he will collaborate with several other departments on the identification and classification of cell types in the mouse nervous system.
Work within the Molecular Genetics team on experimental design, execution, and research associate training in order to generate large-scale single cell transcriptome datasets.
Work with Modeling, Analysis and Theory team to timely and iteratively analyze single cell data from the internal single cell transcriptomics pipeline and facilitate generation of cell type taxonomy.
Design and execute validation and follow-up experiments to place the transcriptomics results in the neurobiological context.
Write and publish manuscripts, grant progress reports and grant applications.
Present work internally and externally at conferences.
Evaluate new single cell RNA-seq platforms and techniques.
Work with Electrophysiology and Neuroanatomy teams to facilitate data organization and integration in an effort to create multimodal neuronal taxonomy.
Ph.D. in life sciences or computational biology (e.g., Neuroscience, Genomics, Genetics, or related field).
Knowledgeable in genomic data generation from primary tissues (rodent handling, dissection, single cell collection, molecular biology, and next generation sequencing).
Knowledgeable about developmental neurobiology and systems neurobiology
Knowledgeable about RNA-seq, ATAC-seq and/or ChIP-seq data
Proficiency in R and Linux shell scripting.
2+ years of experimental experience in genomic data generation from primary tissues (rodent handling, dissection, single cell collection, molecular biology, and next generation sequencing).
2+ years of experience working in a rodent model system studying a neurobiological problem in vivo (e.g., developmental neurobiology, systems neurobiology).
2+ years of computational experience working with RNA-seq, ATAC-seq and/or ChIP-seq data, preferably at the single cell level.
Ability to develop, test, implement, and share new experimental and computational tools quickly, in an iterative manner, after feedback from experimental, data production, and analysis teams.
Experience with additional programming languages (Perl, Python, Matlab) preferred.
Exceptional oral and written communication skills.
Ability to work independently as well as part of a team to meet aggressive timelines in a collaborative environment.
It is the policy of the Allen Institute to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state or local law. In addition, the Allen Institute will provide reasonable accommodations for qualified individuals with disabilities.
Manager, Cell Therapy And Cell Engineering Facility (Ctcef)
At Memorial Sloan Kettering (MSK), we're not only changing the way we treat cancer, but also the way the world thinks about it. By working together and pushing forward with innovation and discovery, we're driving excellence and improving outcomes.
For the 28th year, MSK has been named a top hospital for cancer by U.S. News & World Report. We are proud to be on Becker's Healthcare list as one of the 150 Great Places to Work in Healthcare in 2018, as well as one of Glassdoor's Employees' Choice Best Place to Work for 2018. We're treating cancer, one patient at a time. Join us and make a difference every day.
The Operations and QA Manager, Cell Therapy and Cell Engineering Facility (CTCEF) directs, plans and actively participates in daily functions of the Cell Therapy and Cell Engineering Facility to ensure efficient and effective operations and compliance with all aspects of quality assurance and facility operations in a highly regulated environment. The CTCEF is responsible for the production of clinical cellular products for Phase I/II clinical trials.
Responsible for maintaining the CTCEF facility in GMP compliance
Supervises a team of 5 staff members who operate the facility, including the facility manager
Oversees gowning and personnel monitoring procedures
Oversees environmental monitoring procedures
Oversees operation and validation of equipment
Oversees qualification and quarantine of raw material
Oversees the database for the management and inventory of raw materials and clinical products.
Oversees and contributes to inspections, audits and certification of suppliers
Oversees and coordinates the multi-user GMP facility operations
Oversees facility user's qualifications (e.g training, workflow, reagents qualifications, SOPs, process validations)
Oversees the integration of multi-users raw material inventory supplies for manufacturing
Oversees production scheduling and facility turnover (e.g cleaning, room and equipment certifications)
Oversees the Equipment monitoring alarm 24/7 (> 400 units) including on-site and off-site storage of cellular clinical products
Responsible for developing and maintaining the CTCEF quality management system to ensure that the facility and processes are compliant with cGMP/FDA regulations.
Supervises one Technical writer who operates MasterControl
Develops and maintains the CTCEF quality manual
Develops and maintains the CTCEF quality management system to ensure facility and processes compliance with current 21CFR/FDA regulations and FACT/ Immune Effector Cells regulations
Oversees operation and maintenance of MasterControl: controlled documentation life cycle (e.g SOPs, MPCRs), training, deviation, change control, quality improvement, validation, audit
Oversees completion and documentation of training and on-going competency
Oversees and supports non-compliances
Prepares the facility for external audit
Oversees and conducts internal audits
Insures readiness of facility for FDA inspections
Contributes to Gene Transfer and Somatic Cell Engineering (GTF) user group production runs related documentation
Supervises a team of 2 staff members who coordinate production runs and related compliant documentation
Supports issuance of Batch Production and Controlled Records (BPCR)
Supports and coordinates the assembly, timely completion and reviewing of the BPCR
Contributes to MPCR approval
Development and implementation of new manufacturing procedures
Liaise with the Director, the Production manager and the Research and Technology Mgmt group for effective integration and FDA compliance of new procedures in the core facility.
Assists production teams with process qualifications and validations documentation
Contributes to the preparation of documents including the CMC section of INDs submitted to the FDA
Delivery of cellular products for infusion of cellular products
Helps the QA Coordinator, QC and Production staff members to coordinate tthe release and delivery of cellular products to the hospital staff in compliance with FACT/IEC regulations
Prepares budgets, chargeback invoices, facility user invoices and helps establish contract manufacturing services
Master's Degree with 5-10 years of related experience in cGMP operations, laboratory management or work in controlled therapeutic manufacturing environments is highly preferred.
Applicants must be familiar with the principles of quality assurance and FDA regulations.
excellent communication, interpersonal skills and organizational skills
- team leader, strong supervisory and leadership skills
- project management
- equipment qualification and validation
- writing reports and computer software skills #LI-SB1
MSK is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sexual orientation, national origin, age, religion, creed, disability, veteran status or any other factor which cannot lawfully be used as a basis for an employment decision.
Federal law requires employers to provide reasonable accommodation to qualified individuals with disabilities. Please tell us if you require a reasonable accommodation to apply for a job or to perform your job. Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment.
Quality Cell Leader, 1St Shift
The sky has no limits.
Flight is an instrument of human progress. It not only gets people where they want to go, it carries humanity to places it never thought possible.
At Pratt & Whitney, you'll be part of an evolving, globally diverse company that's moving fast to shape the future of aviation. Customers all over the world depend on our technology and the people behind it. As part of the team at Pratt & Whitney, you'll help answer today's challenges in powered flight while shaping and supporting tomorrow's solutions.
Responsible for leading a group of hourly Inspectors in a dynamic manufacturing environment. Responsibilities include allocating work, assigning manpower and providing leadership for employees in the areas of EH&S, ACE, Quality and continuous improvement initiatives.
Typical duties include, but are not limited to the following: interfacing with the other shift supervisor and management on daily key action activity (carryover); lead daily toolbox meetings, provide effective communications with members of management on activity status and plans; provide employee team development that is responsive to program requirements and changes.
Establish standards and expectations for work effort and performance for subordinates. Give consistent feedback on performance to those standards. Effectively coach employees to improve performance when needed.
Perform administrative functions as related to Bargaining Unit employees including maintaining training, quality and attendance records.
Establish work schedules taking into account Customer requirements, resource availability and other priorities
Associate Scientist/Scientist - Cell And Tissue Engineering
The Job Details are as follows:
Develop, implement, and execute analytical strategies to assess the biology of epithelial, endothelial, mesenchymal, and other cell types and to optimize their utility in lung tissue engineering applications.
Key Accountabilities /
Prepare human and non-human organs, tissues, scaffolds, and cells for experimentation using appropriate surgical handling techniques, dissection, cannulation and suturing; utilize sterile technique when indicated
Design and perform experiments to evaluate cell behavior, health, morphology, differentiation, etc. in tissue engineered lung constructs using a combination of 2D and 3D cell culture and recellularization systems
Design and perform experiments to test the cellular effects of mechanical stimuli, such as vascular fluid flow and mechanical ventilation, on endothelial, epithelial and other cell types in tissue engineered lung constructs
Develop strategies to optimize cellular morphology and phenotype in engineered lung constructs to best facilitate pulmonary airway and vascular function
Operate and maintain all equipment necessary for lung construct assessment including bioreactor systems, mechanical ventilators, and computer control systems
Record all laboratory data in the in-house data management system(s)
Regularly present and discuss data with laboratory staff and program leaders
Follow proper procedures regarding laboratory safety, use of personal protective equipment, and handling of biohazard materials, including human or animal cells and tissues
PhD in life sciences or medical field with focus on pulmonary biology, molecular medicine, and/or endothelial or epithelial molecular mechanisms
1-4 years of post-doctoral training in pulmonary biology, molecular medicine, and/or endothelial or epithelial molecular mechanisms
Experience interrogating cellular or molecular phenotype or function
Facility with appropriate word processing, spreadsheet, presentation and related standard software
Experience with laboratory instrumentation and data software
Preferred Knowledge, Skills, and Abilities:
Facility with appropriate word processing, spreadsheet, presentation and related standard software
Experience with laboratory instrumentation and data software
Good team member skills; must work well with others
Good written and oral communication skills
Ability to initiate and manage day-to-day tasks effectively
Ability to organize and present data
Ability to independently follow experimental methods and protocols
United Therapeutics Corporation is an Equal Opportunity/Affirmative Action Employer - EOE Minorities / Females / Protected Veterans / Individuals with Disabilities
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