Cell Repairer Job Description Sample
Postdoctoral Scholar Opportunity For Regenerative Stem Cell Therapy For Spinal Cord Injury Repair
A post-doctoral position is immediately available in the McDevitt Laboratory for Engineering Stem Cell Technologies at the Gladstone Institutes in San Francisco, CA. This opening is for a newly funded project that examines the potential of excitatory spinal interneurons differentiated from human pluripotent stem cells as a novel regenerative cell therapy to treat spinal cord injury (SCI). This individual would be primarily responsible for conducting and analyzing cell transplantation studies in a mouse model of SCI as well as in vitro screening studies to optimize directed differentiation methods.
This project is part of the overall focus of the laboratory to engineer novel technologies that translate the therapeutic potential of stem cells into viable products for regenerative medicine applications. We are seeking a highly qualified, motivated and talented individual with relevant interests and background expertise to join our interdisciplinary team of researchers.
Qualified candidates must have a Ph.D. in bioengineering and/or a related biomedical science field and a solid track record of research productivity evidenced by multiple publications in quality peer-reviewed journals. Prior experience in stem cell culture and differentiation, cell transplantation, neuroscience, histological analysis and microscopy is strongly preferred.
Previous experience with pluripotent stem cell culture, small animal models of SCI, molecular biology and/or genomic analysis would be very beneficial. In addition to strong communication skills, the ability to work independently and effectively as part of a team is necessary to facilitate local and external collaborations with other laboratories.
Please submit a CV including at least 3 references and cover letter describing background experience and future interests to: email@example.com
Scientist I Single Cell Transcriptomic Approaches To Cell Types In The Mouse Nervous System
The Allen Institute for Brain Science, located in Seattle, Washington, is committed to understanding how the brain works and helping to unlock the mysteries of neurological diseases and disorders affecting millions worldwide.
The Allen Institute is seeking an exceptional candidate who will be part of a Seattle-based multidisciplinary team within the Cell Types Program. The successful candidate will participate in high-throughput single cell transcriptome data generation and analysis to support the effort funded by the newly awarded BRAIN grant from the NIH, which aims to define all cell types in the adult mouse brain. The candidate will be a Ph.D. graduate in life sciences or computational biology and will possess strong experimental and computational skills. She/he will collaborate with several other departments on the identification and classification of cell types in the mouse nervous system.
Work within the Molecular Genetics team on experimental design, execution, and research associate training in order to generate large-scale single cell transcriptome datasets.
Work with Modeling, Analysis and Theory team to timely and iteratively analyze single cell data from the internal single cell transcriptomics pipeline and facilitate generation of cell type taxonomy.
Design and execute validation and follow-up experiments to place the transcriptomics results in the neurobiological context.
Write and publish manuscripts, grant progress reports and grant applications.
Present work internally and externally at conferences.
Evaluate new single cell RNA-seq platforms and techniques.
Work with Electrophysiology and Neuroanatomy teams to facilitate data organization and integration in an effort to create multimodal neuronal taxonomy.
Ph.D. in life sciences or computational biology (e.g., Neuroscience, Genomics, Genetics, or related field).
Knowledgeable in genomic data generation from primary tissues (rodent handling, dissection, single cell collection, molecular biology, and next generation sequencing).
Knowledgeable about developmental neurobiology and systems neurobiology
Knowledgeable about RNA-seq, ATAC-seq and/or ChIP-seq data
Proficiency in R and Linux shell scripting.
2+ years of experimental experience in genomic data generation from primary tissues (rodent handling, dissection, single cell collection, molecular biology, and next generation sequencing).
2+ years of experience working in a rodent model system studying a neurobiological problem in vivo (e.g., developmental neurobiology, systems neurobiology).
2+ years of computational experience working with RNA-seq, ATAC-seq and/or ChIP-seq data, preferably at the single cell level.
Ability to develop, test, implement, and share new experimental and computational tools quickly, in an iterative manner, after feedback from experimental, data production, and analysis teams.
Experience with additional programming languages (Perl, Python, Matlab) preferred.
Exceptional oral and written communication skills.
Ability to work independently as well as part of a team to meet aggressive timelines in a collaborative environment.
It is the policy of the Allen Institute to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state or local law. In addition, the Allen Institute will provide reasonable accommodations for qualified individuals with disabilities.
Cell Processing Specialist Car-T Cell Therapy - Morris Plains, NJ
A global healthcare leader, Novartis has one of the most exciting product pipelines in the industry today. A pipeline of innovative medicines brought to life by diverse, talented, performance driven people.
All of which makes us one of the most rewarding employers in our field. We're committed to peak performance, improving the quality of life, and embracing and leveraging diverse backgrounds, cultures and talents to achieve competitive advantage.
The Cell Processing Specialist is responsible for operations on Day 0, cell washing and Harvest processing and for verifying cell processing associates on intermediate processing days of patient derived clinical and commercial cellular immunotherapy products.
Cell processing specialist will also be responsible for the formulation and verification of all media lots. Due to the nature of the starting material (patient cells) this role requires high level of proficiency and ownership of the process and media formulation.
Ownership for the processing of the assigned Patient starting material in the clean room environment
Ability to gown aseptically and work in a clean room environment (ISO 8, 7 and ISO 5) areas for extended periods of time
Day 0, cell washing and Harvest processing with the ability to work with automated equipment such as the CS5 and Sepax
Verification of intermediate process days which include expertise with the wave bioreactor, NC-200 and in process environmental monitoring
Maintains and prepares equipment/environment for use
Proficient in the use of production related IT systems such as SAP, LIMS and MES
Documents all steps in the assigned Batch record in line with GMP requirements
Conduct all necessary processing/verification steps for the assigned lot with highest skill level of aseptic technique
Conduct all necessary processing/verification steps for assigned lots of media with the highest skill level of aseptic technique
Assist on Deviation Investigations and Inspections
Participation in assigned qualification/ validation activities
Responsible for Successful on time completion of required training curriculum comprising of the necessary Global Operating Procedures (GOPs), Standard Operating Procedures (SOPs) and Aseptic Techniques, Gowning Qualifications and other relevant training including HSE for the specific role
Maintains an "audit ready" module
Perform other duties as assigned; ie. batch record review, process streamline improvements, safety walk-thrus
Key Performance Indicators:
Right First Time Batch Record execution
Conformance to schedule
95% training compliance of all associates
Adherence to attendance guidelines and all safety related procedures
No major or critical audit findings pertinent to the ISO 5 & 7 areas
Manufacturing compliance/adherent to all GDP/GMP principles
Aseptic/Cleanroom behavior in accordance with GMP guidelines
Director, Cell Line And Cell Culture Bioprocess Development
Five Prime Therapeutics, Inc. (NASDAQ: FPRX) is a publicly traded, clinical-stage biotechnology company focused on discovering and developing innovative immuno-oncology protein therapeutics to improve the lives of patients with serious diseases. We have an industry-leading and differentiated drug discovery platform. Our comprehensive proprietary libraries of the extracellular proteome, differentiated screening capabilities and protein therapeutic generation and engineering capabilities comprise a unique and powerful IND engine that will continue to generate important development programs. This uniquely positions us to discover novel pathways and targets in immuno-oncology. Our success with our drug discovery platform has led to a pipeline that is on track to more than double to five development programs in clinical trials across multiple indications in 2018. We also have several undisclosed research programs at different points of the target validation and molecule generation phases that have the potential to yield our next wave of development-stage therapeutic biologics. And we continue to fuel this process at the earliest stages with new screens planned this year.
Five Prime is committed to innovation and outstanding science to develop effective new drugs for the treatment of severe diseases. We value our culture of openness, collaboration and productivity. The company is in a strong financial position and has an effective executive team and Board of Directors. Discover more about FivePrime at www.fiveprime.com.
Reporting to the VP Manufacturing Sciences, this position will be responsible for providing strategic input relates to CMC decisions and will contribute significantly to the development and success of the Manufacturing Sciences team. Partner with other functional leaders from Analytical, Formulation, Supply Chain, CMO management and Quality in support of the project teams and of the organization.
This position will lead the Cell line and Cell Culture Bioprocess team for clinical and commercial manufacture of mAbs, fusion proteins and other novel biologics. The responsibilities include development of cell line and cell culture process, production of preclinical supplies at in-house bioprocess pilot plant, oversight of technology transfer to Contract Manufacturing Organizations (CMOs) and support of regulatory submissions. In addition, this individual will be accountable for overall management of the function such as resource planning, employee engagement and workflow enhancement.
Essential Functions and Duties
Key member of the Manufacturing Sciences leadership team to assess and support CMC strategy
Oversee cell line development for the selection of production cell line for master cell bank manufacturing.
Lead cell culture process development, optimization, characterization/validation, scale up and technology transfer to CMO's.
Manage process development experimental design, execution and writing process development plans/reports.
Introduce new technology to enhance workflow and capabilities.
Manage bioprocess suite, trouble-shooting of processes, instrumentation, and equipment to ensure timely in-house manufacturing to support preclinical animal studies.
Provide supervision for technology transfer and oversee CMO activities. Review, or approve batch records and SOPs; address production issues at CMO's in collaboration with quality and regulatory teams.
Acts as a mentor for the junior staff, provide coaching and emphasize best practices.
Partner with QA and Regulatory to support batch releases and regulatory submissions.
PhD in biochemistry, chemical/biochemical engineering or related disciplines
12+ years of in-depth technical experience in cell culture bioprocess development for protein drugs.
Solid knowledge and experiences in mammalian cell culture process engineering and process scale-up/scale-down design is essential.
Leadership experience with proven capability as a successful leader in a strategic multifunctional environment, highly skilled in leading change and people agility
Strong business acumen and critical thinking
Proven experience in process characterization and validation.
Hands on experiences with technology transfer of manufacturing process.
Must be scientifically knowledgeable, team-orientated, and passionate in biopharmaceutical development.
Knowledge of cGMP's, regulatory guidelines, validation practices, and other relevant regulatory requirements.
Excellent interpersonal communication and presentation skills.
At FivePrime, we believe a diverse workforce drives our success as a company. We are always working to create an environment where different backgrounds and viewpoints are valued and celebrated.
FivePrime is an equal opportunity employer. FivePrime makes employment decisions, including in recruitment and selection, without consideration of race, color, national origin, religion, sex, gender, gender identity or expression, sexual orientation, age, veteran status or disability.Please call or reply with any comments.
All your information will be kept confidential according to EEO guidelines.
Postdoctoral Fellow – Cell Line Development/Nanoscale Cell Culture Analytics
Career CategoryPostdoctoralJob Description
The Amgen Postdoctoral Program is committed to providing future scientists with an enriched environment to inspire innovation that will contribute to the development of human therapeutics.
The Cell Line Development group is responsible for the generation of highly productive manufacturing cell lines for Amgen's rich and diverse large molecule pipeline.
We are currently employing next generation nanoscale fluidic devices to miniaturize Cell Line Development processes. This novel technology enables simultaneous isolation, culturing and analysis of thousands of clonal cells lines.
The Postdoctoral Fellow will utilize their biochemistry and immunoassay expertise and work cross functionally with groups across Amgen to develop new high throughput, nanoscale assays to enable characterization of thousands of production cells lines for cell culture performance, protein production and product quality attributes relevant to Amgen's large molecule pipeline.
The assignment length is expected to be 3 years long.
PhD at the time of appointment
PhD at the time of appointment in a life science or engineering discipline
The successful candidate is a highly motivated and self-driven expert in cell biology and biochemistry with a strong publication record
Direct experience developing assays to quantify and characterize proteins
Experience with cell culture, protein purification, cytometry, micro/nanofluidic technology and or other analytical methods
Experience with data analysis and modeling
Proven experience working efficiently in a cross functional, multidiscipline team structure, and ability to execute projects independently
If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.
Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.
As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.
Electrical/Mechanical Technician - Cell Production
Panasonic Corporation is working to manufacture photovoltaic (PV) modules and cells for solar panels at Tesla's factory in Buffalo, New York.
Panasonic's role is to manufacture and supply our SHJ (Silicon Heterojunction) PV cells and modules that feature industry-leading module conversion efficiency and outstanding temperature coefficient characteristics, which result in more power than similarly rated solar panels.
This collaboration makes optimum use of both companies' strengths to enhance the competitiveness of their products, generating a synergy effect between Panasonic's technological and manufacturing expertise in the photovoltaic business and Tesla's strong sales channels, rich creativity and market-leading, cutting-edge innovation.
As a valued partner and strong customer of Panasonic, Tesla is making a long-term purchase commitment for products manufactured at the Riverbend factory.
This is an opportunity that's made to order for a career-minded individual who wants to make a difference and contribute to a more sustainable future based on renewable energy. Join this creative technology collaboration and grow with it as operations continue to expand.
The most successful employees at PESSNY are results driven and able to continuously adapt to an ever-changing startup environment. They report to work on time and never settle for anything less than the best. They work well in a team environment but also have the drive to succeed when they are on their own. A strong focus on fairness and honesty with a humble attitude are what defines our top performers. Is that you?
Currently, PESSNY has an immediate opening available for an Electrical/Mechanical Technician - Cell Production.
What You'll Get to Do:
Key tasks with respect to the Cell Production Department:
Test equipment for functionality or quality.
Perform preventative maintenance on equipment per the guidance of equipment engineers.
Troubleshoot problems with equipment, devices, or products. Repair equipment as necessary.
Monitor and adjust production processes or equipment for quality and productivity.
Assist engineers in developing, building, or testing prototypes or new products, processes, or procedures.
Maintain inventory of job materials.
Set up and verify the functionality of safety equipment.
Install new equipment.
Provide advice or training to other technicians.
- Responsible KPI performance
Support the manufacturing division
Support production activities
What You'll Bring:
Education & Experience:
Engineering-based vocational school, college degree and above
Experience in repairing and managing manufacturing facilities．
Strong awareness for safety
Basic PC operation
Data aggregation and analytical skills
Collaboration with relevant divisions
Knowledge of PLC, hydraulic and vacuum technologies and the ability to diagnose the mechanical, electrical and programming failure of equipment
Have knowledge of chemicals
Explain things logically
Develop interpersonal relationships through various forms of communication (i.e. spoken, written etc)
Ability to respond to inquiries from superiors and employees
Able to lift up to 25 pounds, transporting work
Handles general chemicals and gas used in solar cell manufacturing
Clean Room environment
The noise level of working environment is usually moderate
Shift work (4 groups 2 shift, night shift)
Candidates must be willing to work in a clean room environment, wearing coveralls, hoods, booties, safety glasses and gloves.
No cosmetics shall be worn in the cleanrooms. This includes: lipstick, eye shadow, eyebrow pencil, mascara, eye liner, false eye lashes, fingernail polish, hair spray, mousse, or the heavy use of aerosols, after shaves and perfumes.
This position will require exposure to strong magnets that will interfere with pacemaker/defibrillator function. For safety reasons, candidates with a pacemaker/defibrillator cannot be considered for this position.
In addition to an environment that's as innovative as our products, we offer competitive salaries and benefits.
What We Offer:
Family like environment with an entrepreneurial spirit
Collaborative culture that thrives on innovation and new ideas
Rewards and recognition for great achievements
Growth opportunities for career development
Flexible work arrangements to help balance life and work
Competitive benefits and compensation package
Panasonic is proud to be an Equal Opportunity/Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender identity, sex, sexual orientation, national origin, disability status, protected veteran status, and any other characteristic protected by law or company policy. All qualified individuals are required to perform the essential functions of the job with or without reasonable accommodation.
Pre-employment drug testing is required for safety sensitive positions or as may otherwise be required by contract or law. Due to the high volume of responses, we will only be able to respond to candidates of interest. All candidates must have valid authorization to work in the U.S. Thank you for your interest in Panasonic Corporation of North America.
Location/Division:Buffalo, NY, USAJob Requisition:TT5056
Production Cell Operator (20180090)
Henry Pratt Company is currently a seeking qualified candidate for full time, regular hourly machinist position.Maintain safe operations by adhering to all safety procedures and regulations.Set up and operate Acer CNC mill/d..." />
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Production Cell Operator
Henry Pratt Company is currently a seeking qualified candidate for full time, regular hourly machinist position.
Maintain safe operations by adhering to all safety procedures and regulations.
Set up and operate Acer CNC mill/drill machine, Circular Saw, and Roll Threader.
Inspect product to ensure product meets specifications and to determine need for machine adjustments.
Start-up of machine, monitors operations, makes adjustments as needed, and stops machine when specified amount of product has been produced.
Inspect machine to determine if adjustments or repairs are required.
Read blueprints, shop drawings, specifications, and machining parameters; interpreting geometric dimensions and tolerances (GD&T).
Maintain equipment by completing preventive maintenance requirements; following manufacturer's instructions; troubleshooting malfunctions; calling for repairs.
Document actions by completing production and quality logs.
Accomplish organization goals by accepting ownership for accomplishing new and different requests.
Verify settings by measuring positions, first-run part, and sample work pieces..
Maintain specifications by observing drilling, milling, cutting, and thread rolling operations; taking measurements; detecting malfunctions; troubleshooting processes; adjusting and reprogramming controls; replacing worn tools; adhering to quality assurance procedures and processes.
Document actions by completing production and quality logs.
Other duties may be assigned.
Henry Pratt Company is an Equal Opportunity Employer. Henry Pratt Company offers an excellent salary and benefits package. Current benefit offerings include: medical and dental insurance, 401K plan with company match, Employee Stock Purchase Plan program, short-term and long-term disability benefits, vacation, tuition reimbursement program, company-provided life insurance, supplemental insurance at group rates, and much more.
Candidates must be available for all shifts and possible mandatory overtime.
Familiar with operating the following machines: saw, roll threader and CNC Mill/Drill Machine.
Familiar with Conversational Programming (ie Mazak)
Demonstrated Machine Operations experience; including, but not limited to setting-up machines and adjust the process until parts meet print specification.
Follow established safety practices and procedures.
Follow ISO policies and procedures.
Good mathematical aptitude and knowledge of measuring instruments such as a tape measure, caliper, micrometer, etc.Currently enrolled in a accredited journeyman machinist program or planning to enroll if hired.
Proficiency reading blueprints, sketches, drawings, manuals, specifications, or sample part to determine dimensions and tolerances of finished work piece, sequence of operations, and setup requirements.
Demonstrated attitude which portrays ability to get along with others, function as a team player, accept constructive criticism from their supervisor and follow work rules.
Must be able to lift or move up to 50 lbs.
Ability to use power tools, air tools, and other vibratory tools.
Ability to work from a standing position for extended periods of time.
Ability to work around heavy machinery at times.
Proficient and demonstrated CNC skills
Three or more years of machining experience in a manufacturing environment
Ability to select and use training/instructional methods and procedures appropriate for the situation when learning or teaching new things.
Ability to perform routine maintenance on equipment and determine when and what kind of maintenance is needed.
Ability to determine the kind of tools and equipment needed to do a job.
Every employee is expected to demonstrate the following core values: customer commitment, high-performance culture, fleet of foot, innovation, accountability, integrity, respect for others, teamwork and safety. Incumbent may be asked to perform other duties as required.
Functional / Technical Skills
Drive for Results
Manager, Cell Therapy And Cell Engineering Facility (Ctcef)
At Memorial Sloan Kettering (MSK), we're not only changing the way we treat cancer, but also the way the world thinks about it. By working together and pushing forward with innovation and discovery, we're driving excellence and improving outcomes.
For the 28th year, MSK has been named a top hospital for cancer by U.S. News & World Report. We are proud to be on Becker's Healthcare list as one of the 150 Great Places to Work in Healthcare in 2018, as well as one of Glassdoor's Employees' Choice Best Place to Work for 2018. We're treating cancer, one patient at a time. Join us and make a difference every day.
The Operations and QA Manager, Cell Therapy and Cell Engineering Facility (CTCEF) directs, plans and actively participates in daily functions of the Cell Therapy and Cell Engineering Facility to ensure efficient and effective operations and compliance with all aspects of quality assurance and facility operations in a highly regulated environment. The CTCEF is responsible for the production of clinical cellular products for Phase I/II clinical trials.
Responsible for maintaining the CTCEF facility in GMP compliance
Supervises a team of 5 staff members who operate the facility, including the facility manager
Oversees gowning and personnel monitoring procedures
Oversees environmental monitoring procedures
Oversees operation and validation of equipment
Oversees qualification and quarantine of raw material
Oversees the database for the management and inventory of raw materials and clinical products.
Oversees and contributes to inspections, audits and certification of suppliers
Oversees and coordinates the multi-user GMP facility operations
Oversees facility user's qualifications (e.g training, workflow, reagents qualifications, SOPs, process validations)
Oversees the integration of multi-users raw material inventory supplies for manufacturing
Oversees production scheduling and facility turnover (e.g cleaning, room and equipment certifications)
Oversees the Equipment monitoring alarm 24/7 (> 400 units) including on-site and off-site storage of cellular clinical products
Responsible for developing and maintaining the CTCEF quality management system to ensure that the facility and processes are compliant with cGMP/FDA regulations.
Supervises one Technical writer who operates MasterControl
Develops and maintains the CTCEF quality manual
Develops and maintains the CTCEF quality management system to ensure facility and processes compliance with current 21CFR/FDA regulations and FACT/ Immune Effector Cells regulations
Oversees operation and maintenance of MasterControl: controlled documentation life cycle (e.g SOPs, MPCRs), training, deviation, change control, quality improvement, validation, audit
Oversees completion and documentation of training and on-going competency
Oversees and supports non-compliances
Prepares the facility for external audit
Oversees and conducts internal audits
Insures readiness of facility for FDA inspections
Contributes to Gene Transfer and Somatic Cell Engineering (GTF) user group production runs related documentation
Supervises a team of 2 staff members who coordinate production runs and related compliant documentation
Supports issuance of Batch Production and Controlled Records (BPCR)
Supports and coordinates the assembly, timely completion and reviewing of the BPCR
Contributes to MPCR approval
Development and implementation of new manufacturing procedures
Liaise with the Director, the Production manager and the Research and Technology Mgmt group for effective integration and FDA compliance of new procedures in the core facility.
Assists production teams with process qualifications and validations documentation
Contributes to the preparation of documents including the CMC section of INDs submitted to the FDA
Delivery of cellular products for infusion of cellular products
Helps the QA Coordinator, QC and Production staff members to coordinate tthe release and delivery of cellular products to the hospital staff in compliance with FACT/IEC regulations
Prepares budgets, chargeback invoices, facility user invoices and helps establish contract manufacturing services
Master's Degree with 5-10 years of related experience in cGMP operations, laboratory management or work in controlled therapeutic manufacturing environments is highly preferred.
Applicants must be familiar with the principles of quality assurance and FDA regulations.
excellent communication, interpersonal skills and organizational skills
- team leader, strong supervisory and leadership skills
- project management
- equipment qualification and validation
- writing reports and computer software skills #LI-SB1
MSK is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sexual orientation, national origin, age, religion, creed, disability, veteran status or any other factor which cannot lawfully be used as a basis for an employment decision.
Federal law requires employers to provide reasonable accommodation to qualified individuals with disabilities. Please tell us if you require a reasonable accommodation to apply for a job or to perform your job. Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment.
Cell Technician II - Little Rock, AR
Goodman Networks offers a complete family of solutions to wireless carriers, OEMs, backhaul service providers, and enterprise customers. Additionally, our Field Services division is a valued partner of DIRECTV delivering high quality service installations, maintenance, and upgrades for residential and commercial customers. Solutions and services offered by Goodman Networks help these entities implement new technologies faster, enhance network performance, and improve business results.
Perform routine maintenance, surveillance, and operations on radio frequency/analog/microwave components. Designs test fixtures, analyzes test results, and documents tests performed on components. Assist in the development of lab test procedures. Documents service by recording inspections and maintenance.
Must be analytical and able to trouble-shoot complex network issues in order to isolates trouble for correction.
Manages all trouble tickets base on severity level and performs corrective measures to insure customer SLA levels are being met.
Performs in a SME level capacity to assist other technicians with troubleshooting and training when necessary.
Communicates efficiently with the NOC to insure proper closeout of maintenance tickets.
Performs routine inspection of spares inventory.
Individual must be a self-starter and able to work through multiple tasks simultaneously.
Repairs or replaces damaged or faulty items in a timely manner to ensure maximum network availability.
Performs all components of cell site maintenance including: automatic/manual optimization, antenna testing and results analysis.
Performs testing, acceptance and analysis of DS0, FT1, T1, T3, OC3, and STS1 circuits including: Microwave or SONET systems, CSU, T1 interface devices, Digital Cross Connects and physical cross connects utilizing appropriate test equipment (T-BERD or equivalent)
Ensures power systems are functional which includes performing and analyzing battery routines, performing voltage adjustments and PM's on rectifiers and DC power systems.
Ensures proper maintenance of site buildings and grounds.
Communicates efficiently & effectively with the NOC to insure proper closeout of maintenance tickets.
Performs inspection of microwave systems. Including: performs routine preventive maintenance, equipment alarm analysis, inspection of waveguide pressure and desiccant, annual preventive maintenance on all radio types, advanced troubleshooting, basic installation and acceptance of radio and path alignment with tower crew.
Must work well under pressure situations involving customer outages and catastrophic network events.
Goodman Networks considers applicants for all positions without regard to race, color, religion, creed, gender, national origin, age, disability, genetic information, marital or veteran status, or any other legally protected status.
Ericsson base station equipment experience
1 year minimum Ethernet backhaul/transport test and troubleshooting experience
Knowledge in all aspects of channel addition / removal, base station equipment alarm analysis and hardware troubleshooting
Knowledge of all call processing schemes including ANALOG/CDMA/UMTS/LTE
Familiarity with RF drive test methods and procedures
Working knowledge of MS Office suite is required
A valid Driver's License is required
Pre-employment physical required
High School Diploma
Associates Degree or equivalent experience
Typically requires 3 years of equivalent experience along with related technical training
Ability to lift 60 lbs. required
The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job
Reasonable accommodations may be made to enable individuals with disabilities to perform the essential function.
Ability to hear, understand and respond appropriately to verbal requests made in person and over the telephone in English
Sit, stand, stoop and drive
Be exposed to indoor and outdoor conditions
Ability to travel between job sites daily is a must; frequent overnight travel or longer is also a must
Must be willing to work days/nights/weekends depending on project demands
Maintain a valid driver license
Research Manager I - Immunology & Cell Biology
MacroGenics is a leader in the discovery and development of innovative medicines that utilize our next generation antibody-based technologies. Our team of 300+ dedicated individuals is advancing a pipeline of product candidates to treat patients with cancer as well as various autoimmune disorders and infectious diseases. Our products and platforms have attracted multiple partnerships with leading pharmaceutical companies around the globe.
The Company considers its employees to be its most valuable asset and we are committed to providing opportunities for individuals to learn and grow as a means to further their professional development. MacroGenics' corporate culture promotes an atmosphere of innovation, open communication and teamwork where employees can see firsthand how they contribute to the success of the organization.
Summary of Position
The Research Manager I is responsible for characterizing biologic drug candidates by performing in vitro cell-based bioassays/experiments in the field of immunology, cell biology and oncology, analzying data, and providing interpretations, recommendations and conclusions in a timely and accurate manner. This individual will aslo work closely with other functional groups to provide technical support for processing and analyzing patient blood samples from early phase clinical immunotherapy trials.
Responsibilities and Job Duties
Designs and performs cell based immuno assays/experiments, and ensures data quality and timely execution.
Seeks to understand the broad objectives of the project as well as individual role in achieving those objectives, and modifies experimental plan when required to respond accordingly.
Analyzes research data accurately and interprets research results to answer scientific questions.
Authors assay protocols and experimental procedures incorporating scientific rationale and necessary technical information for assay development, scientific publications and IND submissions.
Provides logistical support to cell biology group for troubleshooting common immunological bioassays.
Operates immunological laboratory instruments including flow cytometer, fluorescent plate reader and cell sorter, and responsible for ensuring the instruments are properly maintained and for notifying the appropriate service providers to provide regular maintenance and/or repair the equipment in a timely manner.
Learns, understands and masters new experimental techniques, and acts as a technical resource for the team and other cross functional groups.
Provides technical and scientific support to other research teams on the processing and handling of human blood samples from early phase clinical immunotherapy trials.
Education & Experience
Bachelors degree in Cell Biology, Immunology or Molecular Biology or biomedical science discipline and a minimum of 10 years of directly related experience; or
Master's degree in Cell Biology, Immunology or Molecular Biology or biomedical sciences discipline with 5 years of directly related experience
Recent experience with human tumor cell line maintenance, PBMC and major lymphocyte population (T, B and NK cells) isolation from human peripheral blood, flow cytometer-based immunophenotyping, culture of human or murine lymphocytes and cell proliferation assays as well as ELISA is required
Knowledge, Skills and Abilities
The individual should be well versed in various analytical methodologies including but not limited to flow cytometry, immunospot, ELISA, and MSD
Excellent mammalian cell or cell line culture skills
Knowledge of human and rodent immune cell purification and manipulation
Knowledge of cell based binding assays, CTL and intracellular staining methodology
Excellent record keeping, organizational, written and verbal skills
Familiar with routine immune functional assays for human or murine immune cell populations
Able to set up assays and conduct technical troubleshooting analysis
Able to analyze data and provide a critical interpretation of results
Work in collaborative way with other members of the highly productive team and research groups
Ability to handle multiple priorities in a fast-paced environment
Strong interpersonal skills for interfacing with other functional groups
Work experience in biotechnology and/or pharmaceutical companies
Strong experience in human or murine B cell, T cell, NK cell and antigen presenting cell functional assays preferred
A strong background and training in cell biology, oncology and immunology
Hands-on operation experience on various instrumentation include flow cytometry, luminex, MSD, plate reader etc.
MacroGenics is proud to be an equal opportunity employer. Employment selection and related decisions are made without regard to race, color, national origin, sex, gender identity, sexual orientation, religion, age, disability, protected veteran status, or any other characteristic protected by federal, state or local law. We are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the employment process, please email firstname.lastname@example.org or call (301) 354-3566 and/or 711 for TTD/TTY service. Equal Opportunity Employer/Veterans/Disabled
For more information about our commitment to equal employment opportunity, please click here.
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