Crystallographer Job Description Sample
Xfel Computational Crystallographer Postdoctoral Scholar
Berkeley Lab's Molecular Biophysics & Integrated Bioimaging Division has an immediate opening for an XFEL (X-ray Free-Electron Laser) Computational Crystallographer Postdoctoral Fellow. The next decade of structural biology at the Linac Coherent Light Source (LCLS) will include groundbreaking advances in time domain protein crystallography, diffuse scattering to observe dynamic motion, and single particle diffraction, and we are developing the data-centered computational methods that will make these advances possible.
What You Will Do: Serial crystallography datasets carry many challenges, in particular the sheer volume of data, and the special treatment required for still-shot Bragg reflections. We are seeking a scientist with strong physical and mathematical intuition who can formulate and code the appropriate algorithms for data processing, and who has the patience and drive to deal with the many experimental uncertainties and sources of noise.
The successful candidate will join a team of developers focused on software for new science, building on a strong pre-existing software foundation, including the DIALS and cctbx.xfel toolkits created here (http://cci.lbl.gov/publications/nick_sauter.html). One focus area is photosystem II, using a combination of time-resolved XFEL-based crystallography and X-ray emission spectroscopy to elucidate the sequence of redox events leading to the release of molecular oxygen. Our Division is involved in all aspects of the project, including experimental design and construction, data collection, software development, and crystallographic analysis. Another critical area is the examination of other metalloenzymes such as nitrogenase.
Crystallography can spatially resolve the absorption edges from distinct metal centers in the catalytic cofactors, and the absorption spectrum will inform us about the electronic environment and valence states of the atoms. XFELs afford us time resolution, and assure the absence of radiation damage, but the anomalous differences must be quantified to better than 1%, thus creating a need for a unique, new software approach. The projects are funded by a combination of NIH and DOE sources.
We also have an ongoing DOE-funded collaboration with SLAC, to scale up the crystallography data analysis pipeline to petascale supercomputers here at NERSC, and eventually to exascale servers in the next decade. This is a great chance for personal growth in a highly collaborative environment, but candidates should come well prepared with a working knowledge of Python and C++, and attendant problem-solving skills. What is Required:
PhD in Biophysics, Bioinformatics, Mathematics, Computer Science, Engineering or Physical Sciences. Familiarity with macromolecular crystallography, other structural biology techniques, or image processing methods. Python and C++ both mandatory.
Experience with modern object-oriented, version-controlled software development, with a team-oriented approach. Excellent oral and written communication skills. Ability to work effectively as part of a cross-disciplinary team.
Demonstrated ability to analyze complex problems with direct supervision, develop strategies to solve specific problems, while running appropriate controls to validate the correct results. The posting shall remain open until the position is filled. Notes: This is a full time, 2 years, postdoctoral appointment with the possibility of renewal based upon satisfactory job performance, continuing availability of funds and ongoing operational needs.
You must have less than 3 years paid postdoctoral experience. Salary for Postdoctoral positions depends on years of experience post-degree. Full-time, M-F, exempt (monthly paid) from overtime pay.
Salary will be predetermined based on postdoctoral step rates. This position may be subject to a background check. Any convictions will be evaluated to determine if they directly relate to the responsibilities and requirements of the position.
Having a conviction history will not automatically disqualify an applicant from being considered for employment. Lawrence Berkeley National Lab, 1 Cyclotron Road, Berkeley, CA. Berkeley Lab (LBNL) addresses the world's most urgent scientific challenges by advancing sustainable energy, protecting human health, creating new materials, and revealing the origin and fate of the universe.
Founded in 1931, Berkeley Lab's scientific expertise has been recognized with 13 Nobel prizes. The University of California manages Berkeley Lab for the U.S. Department of Energy's Office of Science.
Equal Employment Opportunity: Berkeley Lab is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or protected veteran status.
Berkeley Lab is in compliance with the Pay Transparency Nondiscrimination Provision under 41 CFR 60-1.4. Click here to view the poster and supplement: "Equal Employment Opportunity is the Law." SDL2017
Open Date 05/08/2017
Working Title Staff Crystallographer/Instructor
Professional Patient Sensitive Job Code?
Standard Hours per Week
40 Full Time or Part Time?
Work Schedule Summary
Department 00121 - Chemistry
Salt Lake City, UT
Type of Recruitment
Pay Rate Range 47600 to 90400 Close Date
Open Until Filled
Job Summary Staff crystallographer to operate and manage all aspects of the Department of Chemistry X-ray diffraction facility, as well as teach undergraduate classes.
Responsibilities Provide expertise to the faculty, students, and staff in all areas of X-ray crystallography, including diffractometer operation, data acquisition and analysis, and structure refinement. Management of the X-ray facility including, but not limited to operation, maintenance, reports, training, and billing of a Nonius KappaCCD (equipped with a BrukerAPEXIICCDdetector) and a Bruker D8 diffractometers.
Engage in the teaching of undergraduate classes with a teaching load balanced by the needs of managing and operating the X-ray facility. We seek a person with a strong work ethic, and a practical approach who is passionate about delivering highest quality scientific results and teaching outcomes. Additionally, keeping up-to-date with appropriate advances in the field, ensuring good laboratory practice and safety, providing maintenance, including administrative, grant writing, procurement, service on task forces and committees etc.
Minimum Qualifications Bachelor’s degree in an Engineering discipline or a related field, or equivalency; six years experience in scientific research or engineering development; demonstrated communication skills; and a commitment to provide excellent customer service required. Experience should include project or organizational management. Preference is given for an advanced degree in a scientific or engineering field and for publication of original research or project development in peer reviewed scientific journals, recognized professional society or engineering journals.
Preferences Doctorate or equivalent in Chemistry or in an allied field Extensive experience desired in the area of elucidating the structure of small molecules via single crystal X-ray diffraction Candidate should have a documented record of structure determinations through their appearance in scientific journals Documented experience teaching undergraduate courses Strong problem solving skills, and ability to troubleshoot and conduct simple repairs independently or remotely guided by maintenance engineers are required Excellent communication (written and oral), organizational as well as ability to work effectively and efficiently in a multi-cultural environment, and collaborate with team members, lab users, and external service providers are required
Special Instructions Summary Please include at least three (3) professional references with your application.
Additional InformationThe University of Utah is an Affirmative Action/Equal Opportunity employer and is committed to diversity in its workforce. In compliance with applicable federal and state laws, University of Utah policy of equal employment opportunity prohibits discrimination on the basis of race or ethnicity, religion, color, national origin, sex, age, sexual orientation, gender identity/expression, veteran’s status, status as a qualified person with a disability, or genetic information. Individuals from historically underrepresented groups, such as minorities, women, qualified persons with disabilities, and protected veterans are strongly encouraged to apply. Veterans’ preference is extended to qualified applicants, upon request and consistent with University policy and Utah state law.To inquire about this posting, email: firstname.lastname@example.org or call 801-581-2300. Reasonable accommodations in the application process will be provided to qualified individuals with disabilities. To request an accommodation or for further information about University AA/EO policies, please contact the Office of Equal Opportunity and Affirmative Action, 201 S. Presidents Cr., Rm 135, (801) 581-8365 (V/TDD), email: email@example.com .The University is a participating employer with Utah Retirement Systems (“URS”). To be eligible for retirement contributions, you must be hired into a benefit-eligible position. Certain new hires are automatically assigned to theURSretirement plan and other employees with priorURSservice, may elect to enroll in theURSwithin 30 days of hire. Regardless of whether they are hired into a benefit-eligible position or not, individuals who previously retired and are receiving monthly retirement benefits fromURSmust notify the Benefits Department upon hire. Please contact Utah Retirement Systems at (801)366-7770 or (800)695-4877 or the University’s Benefits Department at (801)581-7447 for information.This position may require the successful completion of a criminal background check and/or drug screen.
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